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Two-dimensional polyacrylamide gel electrophoresis database


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Searching in 'USC-OGP 2-DE database' for entry matching: CHM2A_HUMAN




USC-OGP 2-DE database:  CHM2A_HUMAN


CHM2A_HUMAN


General information about the entry
View entry in simple text format
Entry nameCHM2A_HUMAN
Primary accession numberO43633
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Charged multivesicular body protein 2a; AltName: Full=Chromatin-modifying protein 2a; Short=CHMP2a; AltName: Full=Putative breast adenocarcinoma marker BC-2; AltName: Full=Vacuolar protein sorting-associated protein 2-1; Short=Vps2-1; Short=hVps2-1;.
Gene nameName=CHMP2A
Synonyms=BC2, CHMP2
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_4-7 {PLATELET 4-7}
Homo sapiens (Human)
PLATELET_4-7
  map experimental info
 
PLATELET_4-7

MAP LOCATIONS:
pI=5.70; Mw=31195



PLATELET_5-6 {PLATELET 5-6}
Homo sapiens (Human)
PLATELET_5-6
  map experimental info
 
PLATELET_5-6

MAP LOCATIONS:
pI=5.74; Mw=32477
pI=5.68; Mw=32075

Cross-references
UniProtKB/Swiss-ProtO43633; CHM2A_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameCHM2A_HUMAN
Primary accession numberO43633
Secondary accession number(s) B2R4W6 Q3ZTT0
Sequence was last modified on June 1, 1998 (version 1)
Annotations were last modified on March 15, 2017 (version 146)
Name and origin of the protein
DescriptionRecName: Full=Charged multivesicular body protein 2a; AltName: Full=Chromatin-modifying protein 2a; Short=CHMP2a; AltName: Full=Putative breast adenocarcinoma marker BC-2; AltName: Full=Vacuolar protein sorting-associated protein 2-1; Short=Vps2-1; Short=hVps2-1;
Gene nameName=CHMP2A
Synonyms=BC2, CHMP2
Encoded onName=CHMP2A; Synonyms=BC2, CHMP2
KeywordsAcetylation; Coiled coil; Complete proteome; Direct protein sequencing; Endosome; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAF042384; AAC00005.1; -; mRNA
EMBLAJ277113; CAC14310.1; -; Genomic_DNA
EMBLAY364248; AAQ76807.1; -; mRNA
EMBLBT007298; AAP35962.1; -; mRNA
EMBLCR457002; CAG33283.1; -; mRNA
EMBLAK311974; BAG34913.1; -; mRNA
EMBLCH471135; EAW72609.1; -; Genomic_DNA
EMBLBC002502; AAH02502.1; -; mRNA
CCDSCCDS12986.1; -; .
RefSeqNP_055268.1; NM_014453.3; .
RefSeqNP_940818.1; NM_198426.2; .
UniGeneHs.12107; -; .
ProteinModelPortalO43633; -; .
SMRO43633; -; .
BioGrid118091; 51; .
DIPDIP-48533N; -; .
IntActO43633; 34; .
MINTMINT-5005843; -; .
STRING9606.ENSP00000310440; -; .
iPTMnetO43633; -; .
PhosphoSitePlusO43633; -; .
OGPO43633; -; .
EPDO43633; -; .
MaxQBO43633; -; .
PaxDbO43633; -; .
PeptideAtlasO43633; -; .
PRIDEO43633; -; .
DNASU27243; -; .
EnsemblENST00000312547; ENSP00000310440; ENSG00000130724; .
EnsemblENST00000600118; ENSP00000469240; ENSG00000130724; .
EnsemblENST00000601220; ENSP00000472680; ENSG00000130724; .
GeneID27243; -; .
KEGGhsa:27243; -; .
UCSCuc002qti.3; human; .
CTD27243; -; .
GeneCardsCHMP2A; -; .
HGNCHGNC:30216; CHMP2A; .
HPAHPA041153; -; .
HPAHPA042031; -; .
MIM610893; gene; .
neXtProtNX_O43633; -; .
OpenTargetsENSG00000130724; -; .
PharmGKBPA142672111; -; .
eggNOGKOG3230; Eukaryota; .
eggNOGCOG5491; LUCA; .
GeneTreeENSGT00550000074737; -; .
HOGENOMHOG000177218; -; .
HOVERGENHBG107298; -; .
InParanoidO43633; -; .
KOK12191; -; .
OMAIMEQRQE; -; .
PhylomeDBO43633; -; .
TreeFamTF300118; -; .
ReactomeR-HSA-162588; Budding and maturation of HIV virion; .
ReactomeR-HSA-1632852; Macroautophagy; .
ReactomeR-HSA-432720; Lysosome Vesicle Biogenesis; .
ReactomeR-HSA-917729; Endosomal Sorting Complex Required For Transport (ESCRT); .
ChiTaRSCHMP2A; human; .
GeneWikiCHMP2A; -; .
GenomeRNAi27243; -; .
PROPR:O43633; -; .
ProteomesUP000005640; Chromosome 19; .
BgeeENSG00000130724; -; .
CleanExHS_CHMP2A; -; .
ExpressionAtlasO43633; baseline and differential; .
GenevisibleO43633; HS; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0000815; C:ESCRT III complex; IDA:UniProtKB; .
GOGO:0070062; C:extracellular exosome; IDA:UniProtKB; .
GOGO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell; .
GOGO:0016020; C:membrane; IDA:UniProtKB; .
GOGO:0030117; C:membrane coat; IMP:UniProtKB; .
GOGO:0005635; C:nuclear envelope; IDA:UniProtKB; .
GOGO:0031210; F:phosphatidylcholine binding; IMP:UniProtKB; .
GOGO:0019904; F:protein domain specific binding; IPI:UniProtKB; .
GOGO:0000920; P:cell separation after cytokinesis; IMP:UniProtKB; .
GOGO:0016197; P:endosomal transport; TAS:Reactome; .
GOGO:1904903; P:ESCRT III complex disassembly; NAS:ParkinsonsUK-UCL; .
GOGO:0045184; P:establishment of protein localization; IMP:UniProtKB; .
GOGO:0010458; P:exit from mitosis; IMP:UniProtKB; .
GOGO:0016236; P:macroautophagy; TAS:ParkinsonsUK-UCL; .
GOGO:0010324; P:membrane invagination; IMP:UniProtKB; .
GOGO:0007080; P:mitotic metaphase plate congression; IMP:UniProtKB; .
GOGO:0036258; P:multivesicular body assembly; TAS:ParkinsonsUK-UCL; .
GOGO:0060548; P:negative regulation of cell death; IMP:UniProtKB; .
GOGO:1903723; P:negative regulation of centriole elongation; IMP:UniProtKB; .
GOGO:0031468; P:nuclear envelope reassembly; IMP:UniProtKB; .
GOGO:0006997; P:nucleus organization; IMP:UniProtKB; .
GOGO:1903543; P:positive regulation of exosomal secretion; IMP:UniProtKB; .
GOGO:1902188; P:positive regulation of viral release from host cell; IMP:UniProtKB; .
GOGO:0051291; P:protein heterooligomerization; IMP:UniProtKB; .
GOGO:0051260; P:protein homooligomerization; IMP:UniProtKB; .
GOGO:0051258; P:protein polymerization; IMP:UniProtKB; .
GOGO:0015031; P:protein transport; IEA:UniProtKB-KW; .
GOGO:0010824; P:regulation of centrosome duplication; IMP:UniProtKB; .
GOGO:1901673; P:regulation of mitotic spindle assembly; IMP:UniProtKB; .
GOGO:0050792; P:regulation of viral process; IMP:UniProtKB; .
GOGO:0007034; P:vacuolar transport; IEA:InterPro; .
GOGO:0039702; P:viral budding via host ESCRT complex; IDA:UniProtKB; .
GOGO:0019058; P:viral life cycle; TAS:Reactome; .
InterProIPR005024; Snf7_fam; .
PfamPF03357; Snf7; 1; .



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Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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